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Age-related Decline in Osteoblastogenesis and 1α-Hydroxylase/CYP27B1 in Human Mesenchymal Stem Cells; Stimulation by Parathyroid Hormone
With aging, there is a decline in bone mass and in osteoblast differentiation of human mesenchymal stem cells (hMSCs) in vitro. Osteoblastogenesis can be stimulated with 1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] and, in some hMSCs, by the precursor 25-hydroxyvitamin D(3) (25OHD(3)). CYP27B1/1α-hy...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3215854/ https://ncbi.nlm.nih.gov/pubmed/21824271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00735.x |
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