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Histone Deacetylation Mediates the Rejuvenation of Osteoblastogenesis by the Combination of 25(OH)D(3) and Parathyroid Hormone in MSCs from Elders

Vitamin D metabolites are important effectors of bone and mineral homeostasis. Human bone marrow stromal cells (hMSCs) are targets of 1α,25-dihydroxyvitamin D [1α, 25(OH)(2)D] action to promote their differentiation to osteoblasts. Osteoblastogenesis is also stimulated by 25-hydroxyvitamin D [25(OH)...

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Detalhes bibliográficos
Main Authors: Zhou, Shuanhu, Geng, Shuo, Glowacki, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548026/
https://ncbi.nlm.nih.gov/pubmed/22982627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2012.09.002
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