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Caspase-2 and Caspase-7 Are Involved in Cytolethal Distending Toxin-Induced Apoptosis in Jurkat and MOLT-4 T-Cell Lines

Cytolethal distending toxin (CDT) from Actinobacillus actinomycetemcomitans is a G(2)/M cell-cycle-specific growth-inhibitory toxin that leads to target cell distension followed by cell death. To determine the mechanisms by which A. actinomycetemcomitans CDT acts as an immunosuppressive factor, we e...

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Detalhes bibliográficos
Main Authors: Ohara, Masaru, Hayashi, Tomonori, Kusunoki, Yoichiro, Miyauchi, Mutsumi, Takata, Takashi, Sugai, Motoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321583/
https://ncbi.nlm.nih.gov/pubmed/14742531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.871-879.2004
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