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2-deoxy-D-glucose induces oxidative stress and cell killing in human neuroblastoma cells

Malignant cells have a demonstrably greater sensitivity to glucose deprivation-induced cytotoxicity than normal cells (Biochem J 418:29). This has been hypothesized to be due to a higher level of reactive oxygen species (ROs) production in cancer cells leading to the increased need for reducing equi...

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Main Authors: Shutt, Damon C., O'Dorisio, M. Sue, Aykin-Burns, Nukhet, Spitz, Douglas R.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215774/
https://ncbi.nlm.nih.gov/pubmed/20364116
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