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Contribution of CsrR-Regulated Virulence Factors to the Progress and Outcome of Murine Skin Infections by Streptococcus pyogenes
Streptococcus pyogenes with null mutations in the csrRS regulatory locus are highly virulent in mice due to derepression of hyaluronic acid capsule synthesis and exotoxins, e.g., streptolysin S (SLS) and pyrogenic exotoxin B (SpeB). We generated derivatives of a ΔcsrRS strain that also carry deletio...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC321567/ https://ncbi.nlm.nih.gov/pubmed/14742501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.623-628.2004 |
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