Contribution of CsrR-Regulated Virulence Factors to the Progress and Outcome of Murine Skin Infections by Streptococcus pyogenes

Streptococcus pyogenes with null mutations in the csrRS regulatory locus are highly virulent in mice due to derepression of hyaluronic acid capsule synthesis and exotoxins, e.g., streptolysin S (SLS) and pyrogenic exotoxin B (SpeB). We generated derivatives of a ΔcsrRS strain that also carry deletio...

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Detalhes bibliográficos
Main Authors: Engleberg, N. Cary, Heath, Andrew, Vardaman, Kristal, DiRita, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321567/
https://ncbi.nlm.nih.gov/pubmed/14742501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.2.623-628.2004
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