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Bifunctional Anti-Human Immunodeficiency Virus Type 1 Small Molecules with Two Novel Mechanisms of Action

A class of betulinic acid derivatives was synthesized to target two critical steps in the human immunodeficiency virus type 1 (HIV-1) replication cycle, entry and maturation. Each mechanism of HIV-1 inhibition is distinct from clinically available anti-HIV therapeutics. The viral determinants of the...

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Bibliografski detalji
Glavni autori: Huang, Li, Yuan, Xiong, Aiken, Christopher, Chen, Chin Ho
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC321552/
https://ncbi.nlm.nih.gov/pubmed/14742233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.663-665.2004
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