Functional Angucycline-Like Antibiotic Gene Cluster in the Terminal Inverted Repeats of the Streptomyces ambofaciens Linear Chromosome

Streptomyces ambofaciens has an 8-Mb linear chromosome ending in 200-kb terminal inverted repeats. Analysis of the F6 cosmid overlapping the terminal inverted repeats revealed a locus similar to type II polyketide synthase (PKS) gene clusters. Sequence analysis identified 26 open reading frames, inc...

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Autores principales: Pang, Xiuhua, Aigle, Bertrand, Girardet, Jean-Michel, Mangenot, Sophie, Pernodet, Jean-Luc, Decaris, Bernard, Leblond, Pierre
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Chemistry; Biosynthesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC321545/
https://ncbi.nlm.nih.gov/pubmed/14742212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.575-588.2004
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