Functional Angucycline-Like Antibiotic Gene Cluster in the Terminal Inverted Repeats of the Streptomyces ambofaciens Linear Chromosome

Streptomyces ambofaciens has an 8-Mb linear chromosome ending in 200-kb terminal inverted repeats. Analysis of the F6 cosmid overlapping the terminal inverted repeats revealed a locus similar to type II polyketide synthase (PKS) gene clusters. Sequence analysis identified 26 open reading frames, inc...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Pang, Xiuhua, Aigle, Bertrand, Girardet, Jean-Michel, Mangenot, Sophie, Pernodet, Jean-Luc, Decaris, Bernard, Leblond, Pierre
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2004
Soggetti:	Chemistry; Biosynthesis
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321545/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742212/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.2.575-588.2004
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