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Effects of Positively Selected Sequence Variations in Human and Macaca fascicularis β-Defensins 2 on Antimicrobial Activity

The evolution of orthologous genes coding for β-defensin 2 (BD2) in primates has been subject to positive selection during the divergence of the platyrrhines from the catarrhines and of the Cercopithecidae from the Hylobatidae, great apes, and humans. Three peptides have been selected for a function...

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Detalhes bibliográficos
Main Authors: Antcheva, Nikolinka, Boniotto, Michele, Zelezetsky, Igor, Pacor, Sabrina, Falzacappa, Maria Vittoria Verga, Crovella, Sergio, Tossi, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321537/
https://ncbi.nlm.nih.gov/pubmed/14742239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.685-688.2004
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