Effects of Positively Selected Sequence Variations in Human and Macaca fascicularis β-Defensins 2 on Antimicrobial Activity

The evolution of orthologous genes coding for β-defensin 2 (BD2) in primates has been subject to positive selection during the divergence of the platyrrhines from the catarrhines and of the Cercopithecidae from the Hylobatidae, great apes, and humans. Three peptides have been selected for a function...

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Main Authors: Antcheva, Nikolinka, Boniotto, Michele, Zelezetsky, Igor, Pacor, Sabrina, Falzacappa, Maria Vittoria Verga, Crovella, Sergio, Tossi, Alessandro
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2004
Ábhair:
Susceptibility
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC321537/
https://ncbi.nlm.nih.gov/pubmed/14742239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.2.685-688.2004
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