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Cell-autonomous circadian clock of hepatocytes drives rhythms in transcription and polyamine synthesis

The circadian clock generates daily rhythms in mammalian liver processes, such as glucose and lipid homeostasis, xenobiotic metabolism, and regeneration. The mechanisms governing these rhythms are not well understood, particularly the distinct contributions of the cell-autonomous clock and central p...

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Bibliografische gegevens
Hoofdauteurs: Atwood, Ann, DeConde, Robert, Wang, Susanna S., Mockler, Todd C., Sabir, Jamal S. M., Ideker, Trey, Kay, Steve A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215069/
https://ncbi.nlm.nih.gov/pubmed/22042857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115753108
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