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Structure–function analysis of varicella-zoster virus glycoprotein H identifies domain-specific roles for fusion and skin tropism

Enveloped viruses require membrane fusion for cell entry and replication. For herpesviruses, this event is governed by the multiprotein core complex of conserved glycoproteins (g)B and gH/gL. The recent crystal structures of gH/gL from herpes simplex virus 2, pseudorabies virus, and Epstein–Barr vir...

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Detalhes bibliográficos
Main Authors: Vleck, Susan E., Oliver, Stefan L., Brady, Jennifer J., Blau, Helen M., Rajamani, Jaya, Sommer, Marvin H., Arvin, Ann M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215059/
https://ncbi.nlm.nih.gov/pubmed/22025718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111333108
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