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Regulatory T cells inhibit acute IFN-γ synthesis without blocking T-helper cell type 1 (Th1) differentiation via a compartmentalized requirement for IL-10

CD4(+)CD25(+)Forkhead box P3 (Foxp3)(+) regulatory T cells (Tregs) control immune responses to self and foreign antigens in secondary lymphoid organs and at tissue sites of inflammation. Tregs can modify the function of many immune cells and have been proposed to block early proliferation, different...

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Detalles Bibliográficos
Main Authors: Sojka, Dorothy K., Fowell, Deborah J.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3215041/
https://ncbi.nlm.nih.gov/pubmed/22025707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1110566108
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