Transgenic overexpression of γ-cytoplasmic actin protects against eccentric contraction-induced force loss in mdx mice

BACKGROUND: γ-cytoplasmic (γ-(cyto)) actin levels are elevated in dystrophin-deficient mdx mouse skeletal muscle. The purpose of this study was to determine whether further elevation of γ-(cyto )actin levels improve or exacerbate the dystrophic phenotype of mdx mice. METHODS: We transgenically overe...

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Main Authors: Baltgalvis, Kristen A, Jaeger, Michele A, Fitzsimons, Daniel P, Thayer, Stanley A, Lowe, Dawn A, Ervasti, James M
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214766/
https://ncbi.nlm.nih.gov/pubmed/21995957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2044-5040-1-32
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