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Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M(1)dG (3-(2-deoxy-β-D-erythro-pentofuranosyl)pyrimido[1,2-α]purin-10(3H)-one), by accelerator mass spectrometry
Our laboratory is investigating the in vitro and in vivo metabolic processing of endogenously formed DNA adducts as a means of evaluating candidate urinary biomarkers. In particular, we have focused our studies on the metabolism and disposition of the peroxidation-derived pyrimidopurinone deoxyguano...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214661/ https://ncbi.nlm.nih.gov/pubmed/18461974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx800049v |
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