A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants

Identifying the genetic variants that increase the risk of type 2 diabetes (T2D) in humans has been a formidable challenge. Adopting a genome-wide association strategy, we genotyped 1161 Finnish T2D cases and 1174 Finnish normal glucose-tolerant (NGT) controls with >315,000 single-nucleotide poly...

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Main Authors: Scott, Laura J., Mohlke, Karen L., Bonnycastle, Lori L., Willer, Cristen J., Li, Yun, Duren, William L., Erdos, Michael R., Stringham, Heather M., Chines, Peter S., Jackson, Anne U., Prokunina-Olsson, Ludmila, Ding, Chia-Jen, Swift, Amy J., Narisu, Narisu, Hu, Tianle, Pruim, Randall, Xiao, Rui, Li, Xiao-Yi, Conneely, Karen N., Riebow, Nancy L., Sprau, Andrew G., Tong, Maurine, White, Peggy P., Hetrick, Kurt N., Barnhart, Michael W., Bark, Craig W., Goldstein, Janet L., Watkins, Lee, Xiang, Fang, Saramies, Jouko, Buchanan, Thomas A., Watanabe, Richard M., Valle, Timo T., Kinnunen, Leena, Abecasis, Gonçalo R., Pugh, Elizabeth W., Doheny, Kimberly F., Bergman, Richard N., Tuomilehto, Jaakko, Collins, Francis S., Boehnke, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214617/
https://ncbi.nlm.nih.gov/pubmed/17463248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1142382
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