RNA Folding Affects the Recruitment of SR Proteins by Mouse and Human Polypurinic Enhancer Elements in the Fibronectin EDA Exon

In humans, inclusion or exclusion of the fibronectin EDA exon is mainly regulated by a polypurinic enhancer element (exonic splicing enhancer [ESE]) and a nearby silencer element (exonic splicing silencer [ESS]). While human and mouse ESEs behave identically, mutations introduced into the homologous...

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Autores principales: Buratti, Emanuele, Muro, Andrés F., Giombi, Maurizio, Gherbassi, Daniel, Iaconcig, Alessandra, Baralle, Francisco E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC321440/
https://ncbi.nlm.nih.gov/pubmed/14729981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.3.1387-1400.2004
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