Characterization of cryptic rearrangements, deletion, complex variants of PML, RARA in acute promyelocytic leukemia

Acute promyelocytic leukemia (APL) is characterized by a reciprocal translocation t(15;17)(q22;q21) leading to the disruption of Promyelocytic leukemia (PML) and Retionic Acid Receptor Alpha (RARA) followed by reciprocal PML–RARA fusion in 90% of the cases. Fluorescence in situ hybridization (FISH)...

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Detalhes bibliográficos
Main Authors: Amare, Pratibha Kadam, Baisane, Chanda, Nair, Reena, Menon, Hari, Banavali, Shripad, Kabre, Sharayu, Gujral, Sumit, Subramaniam, P.
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214318/
https://ncbi.nlm.nih.gov/pubmed/22090713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6866.86174
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