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Heterotrimeric G proteins, Focal Adhesion Kinase, and Endothelial Barrier Function

Ligands by binding to G protein coupled receptors (GPCRs) stimulate dissociation of heterotrimeric G proteins into Gα and Gβγ subunits. Released Gα and Gβγ subunits induce discrete signaling cues that differentially regulate focal adhesion kinase (FAK) activity and endothelial barrier function. Acti...

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Autori principali: Thennes, Tracy, Mehta, Dolly
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214251/
https://ncbi.nlm.nih.gov/pubmed/21640127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2011.05.004
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