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Heterotrimeric G proteins, Focal Adhesion Kinase, and Endothelial Barrier Function
Ligands by binding to G protein coupled receptors (GPCRs) stimulate dissociation of heterotrimeric G proteins into Gα and Gβγ subunits. Released Gα and Gβγ subunits induce discrete signaling cues that differentially regulate focal adhesion kinase (FAK) activity and endothelial barrier function. Acti...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3214251/ https://ncbi.nlm.nih.gov/pubmed/21640127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mvr.2011.05.004 |
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