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An efficient simulator of 454 data using configurable statistical models

BACKGROUND: Roche 454 is one of the major 2(nd )generation sequencing platforms. The particular characteristics of 454 sequence data pose new challenges for bioinformatic analyses, e.g. assembly and alignment search algorithms. Simulation of these data is therefore useful, in order to further assess...

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Bibliographic Details
Main Authors: Lysholm, Fredrik, Andersson, Björn, Persson, Bengt
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214204/
https://ncbi.nlm.nih.gov/pubmed/22029428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-4-449
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