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Exploring Population Genetic Models With Recombination Using Efficient Forward-Time Simulations

We present an exact forward-in-time algorithm that can efficiently simulate the evolution of a finite population under the Wright–Fisher model. We used simulations based on this algorithm to verify the accuracy of the ancestral recombination graph approximation by comparing it to the exact Wright–Fi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Padhukasahasram, Badri, Marjoram, Paul, Wall, Jeffrey D., Bustamante, Carlos D., Nordborg, Magnus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323826/
https://ncbi.nlm.nih.gov/pubmed/18430959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.085332
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