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Exploring Population Genetic Models With Recombination Using Efficient Forward-Time Simulations

We present an exact forward-in-time algorithm that can efficiently simulate the evolution of a finite population under the Wright–Fisher model. We used simulations based on this algorithm to verify the accuracy of the ancestral recombination graph approximation by comparing it to the exact Wright–Fi...

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Detalhes bibliográficos
Main Authors: Padhukasahasram, Badri, Marjoram, Paul, Wall, Jeffrey D., Bustamante, Carlos D., Nordborg, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2323826/
https://ncbi.nlm.nih.gov/pubmed/18430959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.085332
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