Abnormal Cognition, Sleep, EEG and Brain Metabolism in a Novel Knock-In Alzheimer Mouse, PLB1

Late-stage neuropathological hallmarks of Alzheimer's disease (AD) are β-amyloid (βA) and hyperphosphorylated tau peptides, aggregated into plaques and tangles, respectively. Corresponding phenotypes have been mimicked in existing transgenic mice, however, the translational value of aggressive...

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Detalhes bibliográficos
Main Authors: Platt, Bettina, Drever, Benjamin, Koss, David, Stoppelkamp, Sandra, Jyoti, Amar, Plano, Andrea, Utan, Aneli, Merrick, Georgina, Ryan, Duncan, Melis, Valeria, Wan, Hong, Mingarelli, Marco, Porcu, Emanuele, Scrocchi, Louise, Welch, Andy, Riedel, Gernot
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214038/
https://ncbi.nlm.nih.gov/pubmed/22096518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027068
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