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The Structural Basis of Localizing Polo-Like Kinase to the Flagellum Attachment Zone in Trypanosoma brucei

The polo-like kinase in the deep branching eukaryote Trypanosoma brucei (TbPlk) has many unique features. Unlike all the other polo-like kinases known to associate with the nucleus and controlling both mitosis and cytokinesis, TbPlk localizes to the flagellum attachment zone (FAZ) and regulates only...

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Библиографические подробности
Главные авторы: Sun, Lu, Wang, Ching C.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214037/
https://ncbi.nlm.nih.gov/pubmed/22096549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027303
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