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8-Phenylthio-adenines stimulate the expression of steroid hydroxylases, Ca(v)3.2 Ca(2+) channels, and cortisol synthesis by a cAMP-independent mechanism
The regulation of cortisol synthesis and the expression of genes coding for steroidogenic proteins by 8-substituted cAMP and 8-substituted adenine derivatives were studied in bovine adrenal zona fasciculata (AZF) cells. At concentrations of 10–50 μM, 8-(4-chlorophenylthio)-cAMP (8CPT-cAMP), but not...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213996/ https://ncbi.nlm.nih.gov/pubmed/21810929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00282.2011 |
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