Activation of G protein-coupled estrogen receptor induces endothelium-independent relaxation of coronary artery smooth muscle

Estrogens can either relax or contract arteries via rapid, nongenomic mechanisms involving classic estrogen receptors (ER). In addition to ERα and ERβ, estrogen may also stimulate G protein-coupled estrogen receptor 1 (GPER) in nonvascular tissue; however, a potential role for GPER in coronary arter...

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Autori principali: Yu, Xuan, Ma, Handong, Barman, Scott A., Liu, Alexander T., Sellers, Minga, Stallone, John N., Prossnitz, Eric R., White, Richard E., Han, Guichun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213995/
https://ncbi.nlm.nih.gov/pubmed/21791623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00037.2011
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