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Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1

Chronic activation of proinflammatory caspase-1 in the retinas of diabetic animals and patients in vivo and retinal Müller cells in vitro is well documented. In this study we characterized how elevated glucose and extracellular purines contribute to the activation of caspase-1 in a cultured rat Müll...

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Detalhes bibliográficos
Main Authors: Trueblood, Katherine E., Mohr, Susanne, Dubyak, George R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213916/
https://ncbi.nlm.nih.gov/pubmed/21832250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00265.2011
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