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Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1

Chronic activation of proinflammatory caspase-1 in the retinas of diabetic animals and patients in vivo and retinal Müller cells in vitro is well documented. In this study we characterized how elevated glucose and extracellular purines contribute to the activation of caspase-1 in a cultured rat Müll...

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Hlavní autoři: Trueblood, Katherine E., Mohr, Susanne, Dubyak, George R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213916/
https://ncbi.nlm.nih.gov/pubmed/21832250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00265.2011
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