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In silico modeling of pH-optimum of protein-protein binding

Protein-protein association is a pH-dependent process and thus the binding affinity depends on the local pH. In vivo the association occurs in a particular cellular compartment, where the individual monomers are supposed to meet and form a complex. Since the monomers and the complex exist in the sam...

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Autors principals: Mitra, Rooplekha C, Zhang, Zhe, Alexov, Emil
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213863/
https://ncbi.nlm.nih.gov/pubmed/21287623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22931
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