Genetic variants and disease-associated factors contribute to enhanced IRF-5 expression in blood cells of systemic lupus erythematosus patients

OBJECTIVE: Genetic variants of the interferon (IFN) regulatory factor 5 (IRF5) gene are associated with systemic lupus erythematosus (SLE) susceptibility. The contribution of these variants to IRF-5 expression in primary blood cells of SLE patients has not been addressed, nor has the role of type I...

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Autori principali: Feng, Di, Stone, Rivka C., Program, MD/PhD, Eloranta, Maija-Leena, Sangster-Guity, Niquiche, Nordmark, Gunnel, Sigurdsson, Snaevar, Wang, Chuan, Alm, Gunnar, Syvänen, Ann-Christine, Rönnblom, Lars, Barnes, Betsy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213692/
https://ncbi.nlm.nih.gov/pubmed/20112383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27223
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