Dysregulation of the Polo-Like Kinase Pathway in CD4(+) T Cells Is Characteristic of Pathogenic Simian Immunodeficiency Virus Infection

CD4(+) T-cell dysfunction highlighted by defects within the intracellular signaling cascade and cell cycle has long been characterized as a direct and/or indirect consequence of human immunodeficiency virus (HIV) infection in humans and simian immunodeficiency virus (SIV) infection in rhesus macaque...

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Bibliographic Details
Main Authors: Bostik, Pavel, Dodd, Geraldine L., Villinger, Francois, Mayne, Ann E., Ansari, Aftab A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC321363/
https://ncbi.nlm.nih.gov/pubmed/14722302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.3.1464-1472.2004
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