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Fitness Landscapes: An Alternative Theory for the Dominance of Mutation

Deleterious mutations tend to be recessive. Several theories, notably those of Fisher (based on selection) and Wright (based on metabolism), have been put forward to explain this pattern. Despite a long-lasting debate, the matter remains unresolved. This debate has focused on the average dominance o...

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Detalhes bibliográficos
Main Authors: Manna, Federico, Martin, Guillaume, Lenormand, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213354/
https://ncbi.nlm.nih.gov/pubmed/21890744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.111.132944
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