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Widespread Correlations Between Dominance and Homozygous Effects of Mutations: Implications for Theories of Dominance
The dominance of deleterious mutations has important consequences for phenomena such as inbreeding depression, the evolution of diploidy, and levels of natural genetic variation. Kacser and Burns' metabolic theory provides a paradigmatic explanation for why most large-effect mutations are reces...
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Formato: | Artigo |
Idioma: | Inglês |
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Copyright © 2005 by the Genetics Society of America
2005
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456530/ https://ncbi.nlm.nih.gov/pubmed/15972465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.039016 |
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