Reduction of metastasis using a non-volatile buffer

The tumor microenvironment is acidic as a consequence of upregulated glycolysis and poor perfusion and this acidity, in turn, promotes invasion and metastasis. We have recently demonstrated that chronic consumption of sodium bicarbonate increased tumor pH and reduced spontaneous and experimental met...

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Hauptverfasser: Ibrahim Hashim, Arig, Cornnell, Heather H., Coelho Ribeiro, Maria de Lourdes, Abrahams, Dominique, Cunningham, Jessica, Lloyd, Mark, Martinez, Gary V., Gatenby, Robert A., Gillies, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2011
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213349/
https://ncbi.nlm.nih.gov/pubmed/21861189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-011-9415-7
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