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The Extracellular Region of Lrp4 is Sufficient to Mediate Neuromuscular Synapse Formation
Neuromuscular synapse formation requires an exchange of signals between motor neurons and muscle. Agrin, supplied by motor neurons, binds to Lrp4 in muscle, stimulating phosphorylation of MuSK and recruitment of a signaling complex essential for synapse-specific transcription and anchoring of key pr...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213289/ https://ncbi.nlm.nih.gov/pubmed/22038977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.22772 |
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