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Reversible and Noisy Progression towards a Commitment Point Enables Adaptable and Reliable Cellular Decision-Making

Cells must make reliable decisions under fluctuating extracellular conditions, but also be flexible enough to adapt to such changes. How cells reconcile these seemingly contradictory requirements through the dynamics of cellular decision-making is poorly understood. To study this issue we quantitati...

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Main Authors: Kuchina, Anna, Espinar, Lorena, Garcia-Ojalvo, Jordi, Süel, Gürol M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213189/
https://ncbi.nlm.nih.gov/pubmed/22102806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002273
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