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Dynamical and Structural Analysis of a T Cell Survival Network Identifies Novel Candidate Therapeutic Targets for Large Granular Lymphocyte Leukemia

The blood cancer T cell large granular lymphocyte (T-LGL) leukemia is a chronic disease characterized by a clonal proliferation of cytotoxic T cells. As no curative therapy is yet known for this disease, identification of potential therapeutic targets is of immense importance. In this paper, we perf...

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Autori principali: Saadatpour, Assieh, Wang, Rui-Sheng, Liao, Aijun, Liu, Xin, Loughran, Thomas P., Albert, István, Albert, Réka
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213185/
https://ncbi.nlm.nih.gov/pubmed/22102804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002267
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