The Role of PKR/eIF2α Signaling Pathway in Prognosis of Non-Small Cell Lung Cancer

BACKGROUND: In this study, we investigated whether PKR protein expression is correlated with mRNA levels and also evaluated molecular biomarkers that are associated with PKR, such as phosphorylated PKR (p-PKR) and phosphorylated eIF2α (p-eIF2α). METHODOLOGY AND FINDINGS: We determined the levels of...

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Autori principali: He, Yong, Correa, Arlene M., Raso, Maria Gabriela, Hofstetter, Wayne L., Fang, Bingliang, Behrens, Carmen, Roth, Jack A., Zhou, Yihong, Yu, Liping, Wistuba, Ignacio I., Swisher, Stephen G., Pataer, Apar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213082/
https://ncbi.nlm.nih.gov/pubmed/22102852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024855
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