RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer

We have demonstrated that RNA-dependent protein kinase (PKR) and its downstream protein p-eIF2α are independent prognostic markers for overall survival in lung cancer. In the current study, we further investigate the interaction between PKR and AMPK in lung tumor tissue and cancer cell lines. We exa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Guo, Chengcheng, Hao, Chuncheng, Shao, RuPing, Fang, Bingliang, Correa, Arlene M., Hofstetter, Wayne L., Roth, Jack A., Behrens, Carmen, Kalhor, Neda, Wistuba, Ignacio I., Swisher, Stephen G., Pataer, Apar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484443/
https://ncbi.nlm.nih.gov/pubmed/25798539
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