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An in vitro co-culture model of esophageal cells identifies ascorbic acid as a modulator of cell competition

BACKGROUND: The evolutionary dynamics between interacting heterogeneous cell types are fundamental properties of neoplastic progression but can be difficult to measure and quantify. Cancers are heterogeneous mixtures of mutant clones but the direct effect of interactions between these clones is rare...

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Bibliografske podrobnosti
Main Authors: Merlo, Lauren MF, Kosoff, Rachelle E, Gardiner, Kristin L, Maley, Carlo C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3213018/
https://ncbi.nlm.nih.gov/pubmed/22026449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-461
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