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A comprehensive survey of clonal diversity measures in Barrett’s esophagus as biomarkers of progression to esophageal adenocarcinoma

Neoplastic progression is an evolutionary process driven by the generation of clonal diversity and natural selection on that diversity within a neoplasm. We hypothesized that clonal diversity is associated with the risk of progression to cancer. We obtained molecular data from a cohort of 239 partic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Merlo, Lauren M.F., Shah, Najaf A., Li, Xiaohong, Blount, Patricia L., Vaughan, Thomas L., Reid, Brian J., Maley, Carlo C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004782/
https://ncbi.nlm.nih.gov/pubmed/20947487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0108
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