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A comprehensive survey of clonal diversity measures in Barrett’s esophagus as biomarkers of progression to esophageal adenocarcinoma

Neoplastic progression is an evolutionary process driven by the generation of clonal diversity and natural selection on that diversity within a neoplasm. We hypothesized that clonal diversity is associated with the risk of progression to cancer. We obtained molecular data from a cohort of 239 partic...

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Autori principali: Merlo, Lauren M.F., Shah, Najaf A., Li, Xiaohong, Blount, Patricia L., Vaughan, Thomas L., Reid, Brian J., Maley, Carlo C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004782/
https://ncbi.nlm.nih.gov/pubmed/20947487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0108
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