New Short Term Prediction Method for Chemical Carcinogenicity by Hepatic Transcript Profiling Following 28-Day Toxicity Tests in Rats

We have previously shown the hepatic gene expression profiles of carcinogens in 28-day toxicity tests were clustered into three major groups (Group-1 to 3). Here, we developed a new prediction method for Group-1 carcinogens which consist mainly of genotoxic rat hepatocarcinogens. The prediction form...

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Bibliografiska uppgifter
Huvudupphovsmän: Matsumoto, Hiroshi, Yakabe, Yoshikuni, Saito, Fumiyo, Saito, Koichi, Sumida, Kayo, Sekijima, Masaru, Nakayama, Koji, Miyaura, Hideki, Otsuka, Masanori, Shirai, Tomoyuki
Materialtyp: Artigo
Språk:Inglês
Publicerad: Libertas Academica 2011
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212863/
https://ncbi.nlm.nih.gov/pubmed/22084566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CIN.S7789
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