Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic 1-Nitropropane in F344 Rats

This study was conducted to determine the concordance of results for a pair of structural isomers, 2-nitropropane (2-NP) and 1-nitropropane (1-NP), using the rat medium-term liver carcinogenesis bioassay (Ito test) and previously published long-term carcinogenicity tests. Male F344 rats were given a...

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Detalhes bibliográficos
Main Authors: Doi, Yuko, Tamano, Seiko, Kawabe, Mayumi, Sano, Masashi, Imai, Norio, Nakashima, Hironao, Furukawa, Fumio, Hagiwara, Akihiro, Otsuka, Masanori, Shirai, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: The Japanese Society of Toxicologic Pathology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266355/
https://ncbi.nlm.nih.gov/pubmed/22319232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.24.207
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