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Transfer of in vivo primed transgenic T cells supports allergic lung inflammation and FIZZ1 and Ym1 production in an IL-4Rα and STAT6 dependent manner

BACKGROUND: CD4+ T helper type 2 (T(H)2) cells, their cytokines IL-4, IL-5 and IL-13 and the transcription factor STAT6 are known to regulate various features of asthma including lung inflammation, mucus production and airway hyperreactivity and also drive alternative activation of macrophages (AAM)...

詳細記述

保存先:
書誌詳細
主要な著者: Dasgupta, Preeta, Chapoval, Svetlana P, Smith, Elizabeth P, Keegan, Achsah D
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212823/
https://ncbi.nlm.nih.gov/pubmed/22014099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-12-60
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