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Evidence for More than One Parkinson's Disease-Associated Variant within the HLA Region

Parkinson's disease (PD) was recently found to be associated with HLA in a genome-wide association study (GWAS). Follow-up GWAS's replicated the PD-HLA association but their top hits differ. Do the different hits tag the same locus or is there more than one PD-associated variant within HLA...

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Hlavní autoři: Hill-Burns, Erin M., Factor, Stewart A., Zabetian, Cyrus P., Thomson, Glenys, Payami, Haydeh
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212531/
https://ncbi.nlm.nih.gov/pubmed/22096524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027109
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