The Immunoproteasomes Regulate Lps-Induced Trif/Tram Signaling Pathway in Murine Macrophages

We have proposed the novel concept that the macrophage ubiquitin-proteasome (UP) pathway functions as a key regulator of LPS-induced inflammation signaling. Our findings suggest that proteasome-associated protease subunits X, Y, and Z, are replaced by LMP subunits after LPS treatment of RAW 264.7 ce...

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Main Authors: Reis, Julia, Hassan, Ferdaus, Guan, Xiu Qin, Shen, Jing, Monaco, John J., Papasian, Christopher J., Qureshi, Asaf A., Van Way, Charles W., Vogel, Stefanie N., Morrison, David C., Qureshi, Nilofer
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3212439/
https://ncbi.nlm.nih.gov/pubmed/21455681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-011-9183-7
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