LPS-Induced Formation of Immunoproteasomes: TNF-α and Nitric Oxide Production are Regulated by Altered Composition of Proteasome-Active Sites

Stimulation of mouse macrophages with LPS leads to tumor necrosis factor (TNF-α) secretion and nitric oxide (NO) release at different times through independent signaling pathways. While the precise regulatory mechanisms responsible for these distinct phenotypic responses have not been fully delineat...

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Main Authors: Reis, Julia, Guan, Xiu Qin, Kisselev, Alexei F., Papasian, Christopher J., Qureshi, Asaf A., Morrison, David C., Van Way, Charles W., Vogel, Stefanie N., Qureshi, Nilofer
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119080/
https://ncbi.nlm.nih.gov/pubmed/21455682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12013-011-9182-8
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