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Targeting SRC in glioblastoma tumors and brain metastases: rationale and preclinical studies
Glioblastoma (GBM) is an extremely aggressive, infiltrative tumor with a poor prognosis. The regulatory approval of bevacizumab for recurrent GBM has confirmed that molecularly targeted agents have potential for GBM treatment. Preclinical data showing that SRC and SRC-family kinases (SFKs) mediate i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3212431/ https://ncbi.nlm.nih.gov/pubmed/20947248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2010.08.014 |
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