Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterization, and cytotoxicity studies

Docetaxel (Dtx) chemotherapy is the optional treatment in patients with hormone-refractory metastatic prostate cancer, and Dtx-loaded polymeric nanoparticles (NPs) have the potential to induce durable clinical responses. However, alternative formulations are needed to overcome the serious side effec...

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Bibliographische Detailangaben
Hauptverfasser: Sanna, Vanna, Roggio, Anna Maria, Posadino, Anna Maria, Cossu, Annalisa, Marceddu, Salvatore, Mariani, Alberto, Alzari, Valeria, Uzzau, Sergio, Pintus, Gianfranco, Sechi, Mario
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer 2011
Schlagworte:
Nano Express
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211323/
https://ncbi.nlm.nih.gov/pubmed/21711774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1556-276X-6-260
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