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TASK channel deletion reduces sensitivity to local anesthetic-induced seizures

BACKGROUND: Local anesthetics (LAs) are typically used for regional anesthesia but can be given systemically to mitigate postoperative pain, supplement general anesthesia or prevent cardiac arrhythmias. However, systemic application or inadvertent intravenous injection can be associated with substan...

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Hlavní autoři: Du, Guizhi, Chen, Xiangdong, Todorovic, Marko S., Shu, Shaofang, Kapur, Jaideep, Bayliss, Douglas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3211141/
https://ncbi.nlm.nih.gov/pubmed/21946151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3182343660
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